Endocrine Abstracts

Introduction: Graves’ hyperthyroidism is an autoimmune disease sustained by auto antibodies binding to and activating the TSH receptor located on the thyroid follicular cell. The diagnosis of Graves’ hyperthyroidism is based upon clinical symptoms, signs and laboratory tests confirming the presence of thyrotoxicosis, positive thyroid peroxidase (TPO) and less commonly thyroglobulin (Tg) antibodies, and finally, positive serum TSH receptor antibodies (TRab). Recently ...

Introduction: Insulinoma is a rare tumor, with peak incidence at 30 -60 years of age and more frequent in women. It is associated with a myriad of clinical manifestations: from clearly defined adrenergic and neuroglycopenic symptoms to asymptomatic hypoglycemia. We present the case of a 20-year-old patient with pancreatic insulinoma, which was surgically resected only after her second hospitalization due to repeated negative imaging.Case presentation: A ...

Introduction: Graves’ disease is an autoimmune disease that leads to a generalized over activity of the entire thyroid gland (hyperthyroidism). It is caused by TRAb thyrotropin receptor antibodies (TRAb), which bind to receptors on the surface of thyroid cells and stimulate those cells to overproduce and release thyroid hormones. Subacute thyroiditis is presumed to be caused by a viral infection or a postviral inflammatory process. It is a self-l...

Acromegaly is a rare disorder with a high morbidity and mortality rate. The diagnosis is typically prolonged over time due to a slow and hidden development of the disease. Current medical therapy for the treatment of acromegaly involves the administration of somatostatin analogues that effectively suppress excess hormone secretion. The objective of this study was to investigate the efficacy of octreotide therapy in acromegalic. A total of 32 patients have been treated with Oct...

Objective: The purpose of this study was to investigate the 25-hydroxyvitamin (25(OH)D3) levels in general population.Introduction: Vitamin D is important for normal bone health. Vitamin D deficiency is a well-known cause of rickets in children and osteomalacia in adults, and it is also of importance for development of osteoporosis. Beyond this, vitamin D deficiency is suggested as a contributing factor in the development of several other diseases and co...

Management of calcium disorders can be a real challenge during the different stages of acute kidney injury complicating rhabdomyolysis.Aim: The aim of this presentation is to present a clinical case diagnosed with rhabdomyolysis, which was complicated by severe hypocalcemia during the acute phase and later on during the recovery phase with hypercalcemia.Case presentation: We present a female patient, 57 years old, who presented to ...

Background: Worldwide, depression is the second-leading cause of disability and diabetic patients have more chances to develop depression compared to non-diabetic people. The aim of our study is to estimate the prevalence of depression among type 2 diabetes patients and to investigate the sociodemographic and clinical factors associated with the presence of depression among these patients in Regional Hospital of Durres, Albania.Methods: Through a cross-s...

We would like to report the case of a 45-year-old woman who came to our emergency department two months ago complaining of exhaustion, vomiting, and stomach pain. In the last three weeks, she had three admissions to the ER due to vomiting. She did not have any chronic illnesses, and her only medication for the vomiting was oral electrolytes. In the last two months, she claims to have lost four to five kilograms. The physical examination showed tachycardia (135 beats per minute...

Introduction: Friedreich ataxia (FA) is a multisystem autosomal recessive disease with progressive clinical course involving the neuromuscular and endocrine system. Individuals with FA have an increased risk of developing diabetes. In FA-associated diabetes, both insulin deficiency and insulin resistance have been reported. We present a case with FA, presented with diabetic ketoacidosis (DKA) as the first presentation of diabetes mellitus.Case Presentati...

It is well known nowadays the positive effect that early detection of prediabetes has in preventing and postponing the diabetes onset. The aim of our study is to explore the diabetes prevalence in Albania and to identify and stratify the population at risk for developing diabetes.Material and methods: A large scale multicentre screening was performed in Albania as part of a National Campaign. 15744 patients were consecutively recluted. The following data...